Currently I am using the following:
JaxTeller's Harsher Death and Food Penalties, 2x increase spawning rate
Khaine's HP bars and wandering hordes
My own modlet that I am currently testing / modifying that removes recipe unlocks via progression, nerfs T0 equipment, reduces the chances of finding Q3Plus equipment in loot, makes changes to traders (only Q6 equipment at higher prices, different hours of operation), and brought back Q6 crafting (requires a new perk to spend points into as I nerfed the other perks to T1-Q3, T2-Q2, T3-Q1 max).