My settings for this are. .difficulty Nomad,, 90 min days,, 64 max alive blood moon and zombies at jog during day and default speed for both night and blood moon along with feral sense active all the time..
I Love the town layouts and better graphics but there seems to be an overabundance of loot for certain things and getting high tier items very quickly. there are things which have changed for the worse in terms of difficulty and how the game is played. I will also say that most of the problems are them trying to balance a game for both single and multi-player..atleast that's what it looks like to me.
Food in single player is not an issue at all with the over abundance of small animals, farms, vending machines and traders to get food from. Also people saving canned goods for recipes which they may never find can lead to food problems but that's outside the pimps control for people doing weird things.
Infection should be a concern as I have seen a few people complaining about how difficult it is to find honey or antibiotics which is good. Way to many people want this game to be as easy as possible with little to no threats from the zombies.
Pipe machine gun weapon along with the ridiculous amount of ammo found needs serious balance. It was insane that on day 7 having a tier 6 pipe machine gun with mods can out classing a tier 3 machine gun think it was called the tactical assault rifle. The pipe machine gun weapon along with any melle weapon is enough to get you through an entire play through. The amount of ammo found is also a bit high along with zombie bags dropping tons of ammo especially the shotgun ammo. Again this might be a single player problem.
An easy solution to some of these problems would be more settings to change in the advanced tab. From zombie damage to crafting costs for items to even how fast crops grow or how much they yield to even how often the trader and vending machines restock. It works fine for other games and I feel this would solve alot of issues as far as multi-player and single player goes when it comes to certain things.
Bit of a long read but this might entertain ya on the toilet. Hope your legs don't fall asleep.