I might sympathize with the argument against resetting POI's if the POI's layouts were challenging at all or if POI's themselves were rare.
There are so many POI's clumped together and each has a loot room with a chest so it's not like getting double loot from a reset is really getting you extra loot you couldn't otherwise get.
When the feature was introduced I did reset the POI to loot twice. I don't do that anymore because I realized it was not worth the time. Better to loot once and run back to the trader for another quest for more XP. I can get the same loot from any POI in the area so it's a waste of time to loot twice while questing.
Also knowing the "layout" of a POI is really no help to me at least. I just run though and kill everything on the way. Zombies in this game are not really challenging at all once you have a gun. I just assume a zombie is around every turn so I'm not really surprised when it is actually true.
I'm talking about vanilla settings with no mods of course. On vanilla settings I have yet to be killed by zombies inside a POI. Unless it was a zombie horde that crashed through the house from the outside trapping me. It's not that I'm so good at the game, rather it's the game is pretty easy on vanilla settings.
If you adjust settings or mod things then that's on you not the game.