In this case, you'd provide two patch files, then just create a zip file with both patches in them. The Launcher will find, and apply all the 7D2DPatch patches.
You can mix-and-match patches, and full updates to the DLLs. Such as, the Assembly-Sharp DLL is around 4 megs, so you could add the full DLL file, and a patch file for the resoruces.assets file, and the launcher will install them both as expected. Or you could apply a patch for the DLL, and include both patches.