My character wiped my brow and I could already see Trader Jen off in the distance not 100 meters away. Sick start. I spent several in-game hours gathering resources before visiting my local merchant, looted her compound, and took a clear quest. I ended up settling in a farm house across the street. I was confused how to enter it at first, but everything clicked when I spotted the other house next door. In between and connecting both buildings was a flooded underground tunnel full of snakes. At first I thought I was being attacked by invisible zombies, it gave me quite a fright. Free meat though.
I have Feral Sense set to "All" and it is bloody fantastic. Even so much as looking down the sights of my gun alerts the undead to my presence. For the first time in years I spent my night in the attic of a POI in the dark and unmoving, and still the zombies detected me. After a few moments of bashing against the door they left me alone.
I've had a lucky streak of finding antibiotics. Two stumps granted me honey during the early parts of the morning, an antibiotic was contained in a zombie loot bag, and I honestly forgot where I looted them, but I also have two herbal antibiotics stored away in my meds chest.
Weapons wise, I looted two quality level 4 pipe rifles in the place I'm staying at. Ammo has been alright, I'm on day 6 right now and I have roughly 100 9mm, 7.62, and shotgun shells.
Food hasn't been so much of an issue beyond day 1. A couple of buried supplies netted me some meat and hobo stews and a blueberry pie. I found the grilled meat recipe in a filing cabinet on day 2 (along with the pumpkin pie recipe and the chili dog recipe in the same loot raid), and chickens have been plentiful enough. I've run into a few bucks and a couple of wild boars - thanks to the insane buff bows/crossbows received, them wild pigs are no longer death on legs in the early stages of the game.
The town generation is amazing. It genuinely feels like this place was lived in at some point, rather than a random hodgepodge of buildings slapped together on barren roads.
Whoever did the new sunrises/sunsets, I give you a round of applause.
Edit: And I just found a Bob's Boars POI.