Universities could be an ultimate goal, but you could make each building separately (the library, the pool, the dorms, the cafeteria...).
Worst case scenario, these are still valid POI on their own.
I had this fantasy about a pool, with like a sunny nice side on top and a dark side with the machinery and stuff underneath.
I tried once, but I suck so much at building, it didn't pan out.
I'll try to give it another go at some point.