I misunderstood "seed" in PREGEN6K, and mistook the Game Title for a seed, which I now see it is not, since I'm trying a full RWG using advanced settings now, and see the Seed input appear where it is missing when using PREGEN. The above error is still persistent using PREGEN. I'll comment again after trying the RWG advanced. I'm also switching to Windowed mode.
Note above that I updated my nVidia display drivers after getting that crash twice, and on launching after the update, the crash persisted.